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overhead shot of Cajun Meatball Subs on a platter with a baking sheet with cooked meatballs on it and mayo and relish off to the side

Cajun Meatball Subs

Meatball subs get a spicy upgrade with these Cajun Meatball Subs. Add some jalapenos, crack a cold Cerveza, and dinner is served.
Course Main Dish
Cuisine Beef, Food to Drink to, Sandwich
Keyword beef, sandwich
Prep Time 5 minutes
Cook Time 30 minutes
Servings 5 sandwiches


  • food processor


  • 1-1/2 pounds ground beef I use 80/20
  • 1/4 cup bread crumbs
  • 1/4 cup milk
  • 1 egg
  • 1/4 tsp pepper
  • 1/4 tsp cumin
  • 1/2 tsp salt
  • 1/4 tsp onion powder
  • 1/2 tsp garlic powder
  • 1 tsp Cajun seasoning

Vinegar-Based Relish

  • 1 medium carrot
  • 2 medium radishes
  • 1 handful cilatro leaves
  • 1/4 tsp salt
  • 1/4 tsp pepper
  • juice of half a lime
  • 1/4 tsp sugar
  • 1/4 tsp white vingar

Spicy Mayo Sauce

  • 1/4 cup mayonnaise
  • 1/2 tsp Cajun seasoning
  • 1 tsp hot sauce


  • Preheat the oven to 375 degrees.
  • In a bowl add the breadcrumbs and milk and let soak for 5 minutes.* Then add the ground beef (I use 80/20), egg, and spices. Using your hand or a wooden spoon and mix everything together.
  • Cover a baking sheet with parchment paper.
  • Form the beef mixture into palm-sized balls. Roll in both hands to form them evenly then add to the baking sheet.
  • Add the meatballs to the oven and bake for 30 minutes.

Vinegar-Based Relish

  • Gather up the carrots, radishes, green onion, cilantro, and lime.
  • In a food processor, chop the ingredients. Once everything is into small bites put the ingredients into a bowl then add the salt, pepper, sugar, and vinegar.

Spicy Mayo Sauce

  • In a small bowl mix the mayonnaise, Cajun seasoning, and hot sauce.
  • Put both the relish and mayonnaise topping into the refrigerator while you wait for the meatballs to cook.
  • Cut the buns in half, add the relish, 3 meatballs per sub, and drizzle with the spicy mayo, and top with slices of pickled jalapenos. Enjoy!


*As I pointed out in my recipe for Baked Meatballs, soaking the breadcrumbs and milk before adding the other ingredients is the key to making the best meatballs that stay moist.